![]() This will only be detected if a strategy is followed and a database maintained.Consistency of data and results will lead ultimately to the reduction in costs as will a reduction or avoidance of technical errors. Any difficulties with the strategy may be assessed from data that are carefully maintained.If assays are changed over the course of time it may become evident that there is common false reactivity among samples. Therefore better diagnoses will be given to patients.Databases will be more useful if tests are used consistently. The staff will become more familiar with interpretation procedures.Similarly, the clarity of reported results will be consistent and easier to understand. Consistency of results If a strategy is followed the results will be more consistent because technical staff will be more familiar with assays and procedures. Log books or computer records can be consistent. The Importance of Maintaining a Strategy.Consistency of Laboratory RecordsThe records can be set up consistently and therefore data will be in better order If a strategy is carefully followed, laboratory records will be more easily maintained.The predictive values of the strategies will change with the prevalence. Each test used in the strategy should employ a different principle and different antigen preparation.The strategy selected also depends on the prevalence of HIV infection within the population being tested. The strategies rest entirely on assays that may be conducted by screening laboratories.It is emphasised that tests must be carefully selected. These strategies are designed to avoid the use of the costly and poorly standardised Western Blot. WHO Recommended Strategies:Because of the cost of supplemental testing WHO has devised and recommended alternative testing strategies.Two genetically distinct population of viruses known to cause AIDS are HIV-1 & HIV-2.HIV-1 is most common type responsible for AIDS in central Africa & HIV-2 in west Africa & India.Antigenic differences is important in serodiagnosisInfection by HIV-1 & HIV-2 may not be identified unless the corresponding type is represented in the test antigen.
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